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Bioassay for determination of fosmidomycin in plasma and urine : Application for pharmacokinetic dose optimisationCHEOYMANG, Anurak; HUDCHINTON, David; KIOY, Deborah et al.Journal of microbiological methods. 2007, Vol 69, Num 1, pp 65-69, issn 0167-7012, 5 p.Article

The methylerythritol phosphate pathway for isoprenoid biosynthesis in coccidia : Presence and sensitivity to fosmidomycinCLASTRE, Marc; GOUBARD, Armelle; PREL, Anne et al.Experimental parasitology. 2007, Vol 116, Num 4, pp 375-384, issn 0014-4894, 10 p.Article

Assessment of in vitro antimalarial interactions between dihydroartemisinin and fosmidomycinCHAIJAROENKUL, Wanna; PRUKTAL, Pattaya; MUHAMAD, Poonuch et al.Southeast Asian journal of tropical medicine and public health. 2007, Vol 38, Num 5, pp 791-795, issn 0125-1562, 5 p.Article

Modifications around the hydroxamic acid chelating group of fosmidomycin, an inhibitor of the metalloenzyme 1-deoxyxylulose 5-phosphate reductoisomerase (DXR)ZINGLE, Catherine; KUNTZ, Lionel; TRITSCH, Denis et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 21, pp 6563-6567, issn 0960-894X, 5 p.Article

The Apicoplast: A Key Target to Cure MalariaMACRAE, James I; MARECHAL, Eric; BIOT, Christophe et al.Current pharmaceutical design (Print). 2012, Vol 18, Num 24, pp 3490-3504, issn 1381-6128, 15 p.Article

Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccataPALAZON, Javier; CUSIDO, Rosa M; BONFILL, Mercedes et al.Journal of biotechnology. 2003, Vol 101, Num 2, pp 157-163, issn 0168-1656, 7 p.Article

Recent developments in the field of phosphonic acid antibioticsNEUMAN, M.Journal of antimicrobial chemotherapy (Print). 1984, Vol 14, Num 4, pp 309-311, issn 0305-7453Article

Fosmidomycin resistance in adenylate cyclase deficient (cya) mutants of Escherichia coliSAKAMOTO, Yoshiko; FURUKAWA, Soichi; OGIHARA, Hirokazu et al.Bioscience, biotechnology, and biochemistry. 2003, Vol 67, Num 9, pp 2030-2033, issn 0916-8451, 4 p.Article

1-deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis : Towards understanding mycobacterial resistance to fosmidomycinDHIMAN, Rakesh K; SCHAEFFER, Merrill L; BAILEY, Ann Marie et al.Journal of bacteriology. 2005, Vol 187, Num 24, pp 8395-8402, issn 0021-9193, 8 p.Article

Fosmidomycin-clindamycin for Plasmodium falciparum infections in African childrenBORRMANN, Steffen; ADEGNIKA, Ayola A; MATSIEGUI, Pierre-Blaise et al.The Journal of infectious diseases. 2004, Vol 189, Num 5, pp 901-908, issn 0022-1899, 8 p.Article

Fosmidomycin, a new phosphonic acid antibiotic. II: 1. Human pharmacokinetics. ― 2. Preliminary early phase IIa clinical studiesKUEMMERLE, H.-P; MURAKAWA, T; SAKAMOTO, H et al.International journal of clinical pharmacology, therapy and toxicology (1980). 1985, Vol 23, Num 10, pp 521-528, issn 0174-4879Article

Synthesis and antimalarial activity of chain substituted pivaloyloxymethyl ester analogues of Fosmidomycin and FR900098KURZ, Thomas; SCHLÜTER, Katrin; KAULA, Uwe et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 15, pp 5121-5135, issn 0968-0896, 15 p.Article

Fosmidomycin analogues as inhibitors of monoterpenoid indole alkaloid production in Catharanthus roseus cellsMINCHEVA, Zoia; COURTOIS, Martine; ANDREU, Francoise et al.Phytochemistry. 2005, Vol 66, Num 15, pp 1797-1803, issn 0031-9422, 7 p.Article

Fosmidomycin for malariaMISSINOU, Michel A; BORRMANN, Steffen; JOMAA, Hassan et al.Lancet (British edition). 2002, Vol 360, Num 9349, pp 1941-1942, issn 0140-6736, 2 p.Article

Molecular epidemiology of malaria in cameroon. XXV. In Vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-D-xylulose 5-phosphate reductoisomeraseTAHAR, Rachida; BASCO, Leonardo K.The American journal of tropical medicine and hygiene. 2007, Vol 77, Num 2, pp 214-220, issn 0002-9637, 7 p.Article

Fosmidomycin plus clindamycin for treatment of pediatric patients aged 1 to 14 years with Plasmodium falciparum malariaBORRMANN, Steffen; LUNDGREN, Ingrid; JOMAA, Hassan et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 8, pp 2713-2718, issn 0066-4804, 6 p.Article

Determination of fosmidomycin in human serum and urine by capillary electrophoresisBRONNER, Stéphane; RENAULT, Corinne; HINTZ, Martin et al.Journal of chromatography. B. 2004, Vol 806, Num 2, pp 255-261, issn 1570-0232, 7 p.Article

The MEP pathway: A new target for the development of herbicides, antibiotics and antimalarial drugsRODRIGUEZ-CONCEPCION, M.Current pharmaceutical design. 2004, Vol 10, Num 19, pp 2391-2400, issn 1381-6128, 10 p.Article

Fosmidomycin, a novel chemotherapeutic agent for malariaLELL, Bertrand; RUANGWEERAYUT, Ronnatrai; WIESNER, Jochen et al.Antimicrobial agents and chemotherapy. 2003, Vol 47, Num 2, pp 735-738, issn 0066-4804, 4 p.Article

Tools for discovery of inhibitors of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase : an approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosaALTINCICEK, B; HINTZ, M; SANDERBRAND, S et al.FEMS microbiology letters. 2000, Vol 190, Num 2, pp 329-333, issn 0378-1097Article

Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomeraseWOO, Youn-Hi; FERNANDES, Roberta P. M; PROTEAU, Philip J et al.Bioorganic & medicinal chemistry. 2006, Vol 14, Num 7, pp 2375-2385, issn 0968-0896, 11 p.Article

Fosmidomycin-clindamycin for the treatment of Plasmodium falciparum malariaBORRMANN, Steffen; ISSIFOU, Saadou; JOMAA, Hassan et al.The Journal of infectious diseases. 2004, Vol 190, Num 9, pp 1534-1540, issn 0022-1899, 7 p.Article

The Methylerythritol Phosphate (MEP) Pathway for Isoprenoid Biosynthesis as a Target for the Development of New Drugs Against Tuberculosis : Protein targets for development of drugs against Mycobacterium tuberculosisOBIOL-PARDO, C; RUBIO-MARTINEZ, J; IMPERIAL, S et al.Current medicinal chemistry. 2011, Vol 18, Num 9, pp 1325-1338, issn 0929-8673, 14 p.Article

Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: An attempt to improve the activity against Mycobacterium tuberculosisANDALOUSSI, Mounir; LINDH, Martin; BJÖRKELID, Christofer et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 18, pp 5403-5407, issn 0960-894X, 5 p.Article

Targeting the methyl erythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery : Inhibition of 1 -deoxy -D-xylulose -5 -phosphate reductoisomerase (DXR) enzymeSINGH, Nidhi; CHEVE, Gweneal; AVERY, Mitchell A et al.Current pharmaceutical design. 2007, Vol 13, Num 11, pp 1161-1177, issn 1381-6128, 17 p.Article

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